Document Type: Review Article


1 Department of Chemistry, Iran University of Science and Technology, Tehran, Iran

2 Department of Chemical Engineering, Payame Noor University, Tehran, Iran

3 Department of Physical Chemistry, Alzahra University, Tehran, Iran



Cardiovascular disease (CVD) represents one of the most important health problems. One of the main risk factors for CVD death is the high cholesterol levels. Statins have been shown to lower low-density lipoprotein (LDL) cholesterol levels and the risk of cardiovascular disease, and are currently the first line of treatment for hypercholesterolemia. Atorvastatin is one of the most effective drugs and is part of the blood lipid lowering drug group. This work studies the mechanism of the use of statin family drugs and atorvastatin to determine the clinical requirements for improving the dermatology and the statins.

Graphical Abstract


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